Doxylamine + Vitamin B6 (Pyridoxine) + Folic Acid is a combination of three medicines: doxylamine, vitamin B6 (pyridoxine) and folic acid, which treats nausea and vomiting associated with pregnancy. Doxylamine is an antihistamine which works by blocking the action of a chemical messenger (histamine), thereby controlling nausea, vomiting, and dizziness. Pyridoxine (vitamin B6) is a form of vitamin B which possesses anti-nausea properties. Folic is also a form of vitamin B which provides essential nutrients.